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ey0018.4-8 | Growth Hormone Therapy: Safety | ESPEYB18

4.8. Longitudinal study on metabolic health in adults SGA during 5 years after GH with or without 2 years of GnRHa treatment

Goedegebuure Wesley J. , van der Steen Manouk , Kerkhof Gerthe F , Hokken-Koelega Anita CS

J Clin Endocrinol Metab, August 2020, 105(8):e2796e2806. doi: 10.1210/clinem/dgaa287. PMID: 32436961The aim of this longitudinal study was to investigate the potential long-term adverse effects of combined GnRHa/GH treatment on metabolic and bone health in short SGA children. Reassuring data are found at 5 years after cessation of GH therapy.Children born small ...

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ey0019.14-11 | Risk and Outcome | ESPEYB19

14.11. SGA-born adults with postnatal catch-up have a persistently unfavourable metabolic health profile and increased adiposity at age 32 years

Goedegebuure Wesley J. , Van der Steen Manouk , Smeets Carolina CJ , Kerkhof Gerthe F , Hokken-Koelega Anita CS

European Journal of Endocrinology (2022)187:1526 doi: 10.1530/EJE-21-1130Brief Summary: This study, PROGRAM32, investigated 287 adults mean age 32 years who had participated 10 years earlier in the PROGRAM study on the metabolic and cardiovascular consequences of low birth weight (LBW). The aim was to investigate the adverse metabolic profile of being small for gestational age with spontane...

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ESPE Yearbook of Paediatric Endocrinology

4.8. Longitudinal study on metabolic health in adults SGA during 5 years after GH with or without 2 years of GnRHa treatment

14.11. SGA-born adults with postnatal catch-up have a persistently unfavourable metabolic health profile and increased adiposity at age 32 years

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